The overall goal of the Animal and Phenotyping Core is to increase the diversity of mouse resources available for aging research. The JAX NSC remains the preeminent aging research center for the development and dissemination of aging mouse models and resources.
Core leader: Gary Churchill
Provide unique animal resources to support aging research
Enhance the characterization of animal models by providing robust and novel assays to evaluate human-relevant health effects of aging.
Implement a first of its kind study to evaluate the effects of reproductive life history on late life health and lifespan in female mice.
Generate primary data and tissue samples for dissemination to the aging community
JAX investigators established models to study the genetics of aging using highly diverse strains, including Collaborative Cross (CC) inbred strains and Diversity Outbred (DO) mice.
A robust phenotyping pipeline ideally suited for large-scale, non-invasive testing of aging mice.