The Jackson Laboratory brings a legacy of expertise in mouse genetics and the development of innovative models for life science research. We offer an unparalleled selection of strains developed and tailored to meet the needs of biomedical researchers. Our curated collections include immune cell humanized mice, immunodeficient mice, models for translational drug development, genetic engineering tools, as well as thousands of industry-standard models.
| Common Name | Strain Number | No. of Publications |
|---|---|---|
| Pep Boy | 002014 | 155 |
| Rag1 KO | 002216 | 83 |
| CX3CR-1GFP KI/KO | 005582 | 65 |
| K18-hACE2 | 034860 | 46 |
| ApoE KO | 002052 | 45 |
| Tau P301S (PS19) | 008169 | 44 |
| p53LoxP | 008462 | 41 |
| DBA2 | 000671 | 39 |
| Ifnar1- | 028288 | 37 |
| Ldlr KO | 002207 | 32 |
*Common and tool models have been removed from this list (ie, B6, GFP, Cre-Lox, NOD).
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Search the JAX Repository for models that recapitulate your disease area of interest. Sort and filter by genotype and phenotype to find your perfect research model.
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JAX mice are delivered in the most state-of-the-art laboratory animal transport systems to ensure that your mice arrive healthy, clean, and unstressed.
Models ranging from nude and SCID to NSG® (NOD scid gamma) are ideal for engraftment protocols, from patient-derived xenografts (PDX) and cancer cell lines (CDX) to immune cell humanization with PBMCs or hematopoietic stem cells (HSCs).
View and select NSG models developed for specific characteristics, including transgenic expression and/or knockout of genes that suit a variety of experimental conditions or research areas.
Immune humanized mice designed to recapitulate in vivo human immune responses. Order CD34+ HSC or PBMC-engrafted platforms for your own research or for enrollment into a JAX Preclinical Service.
JAX offers the most extensive collection of mouse models for neuroscience available, and a comprehensive catalog of human iPSC lines to expand your in vitro experimental protocols. View mouse models for ALS, Friedreich's Ataxia, Muscular Dystrophy, Huntington's, Rett Syndrome, and Alzheimer's Disease.
Select study-ready CD34+ HSC or PBMC humanized NSG or NSG transgenic variants, co-engrafted with the patient-derived xenograft (PDX) tumor specific for your study. The ideal platform for preclinical evaluation of immunotherapeutics.
Antibody discovery mouse platform that enables rapid identification of high-affinity, developable antibodies with broad human sequence diversity. The platform supports the development of monoclonal and bispecific antibodies.
Explore an expanding catalog of models for autoimmune disease research areas: Psoriasis, Lupus, Type 1 Diabetes, Colitis, and GvHD. Our immune CD34+ (HSC) and PBMC cell humanized models are applicable for immunology, autoimmunity, and inflammation studies.
JAX offers the largest collection of cardiovascular disease models available. Start your search here for atherosclerosis & dyslipidemia, hypertension & hypotension, and a range of models that replicate heart disorders for evaluation of potential therapeutics.
Aged mice are invaluable not only in aging research but also other disciplines, including cancer, immunology, cardiovascular disease, and metabolics. JAX aged mice are some of the most extensively studied and published models, making them a trusted choice for high-impact research.