The Jackson Laboratory

Clonal Evolution in Cancer: Heterogeneity, Progression and Therapeutic Resistance

Location: Virtual, hosted by the NCI-Designated Jackson Laboratory Cancer Center 

Explore the forces driving clonal evolution in cancer 

Cancer phenotypes change over time as each tumor cell evolves independently as a genetic unit influenced by its drivers, mutations and microenvironment. These clonal populations compete, adapt and change over time — driving heterogeneity, tumor progression and resistance to therapy.

This free, virtual course will explore cutting-edge technologies and computational approaches that have recently enabled us to analyze and understand the impact of clonal evolution in tumors and provide insights into strategies for overcoming therapeutic resistance. 

Sessions will be held virtually from 12:00 p.m. to 5:00 p.m. ET daily. 

Feb

23 - 24

2026

About

Join us for Clonal Evolution in Cancer: Heterogeneity, Progression and Therapeutic Resistance, a two-day virtual course that brings together leading experts to explore the latest discoveries and technologies that illuminate how cancers change over time. 

Through interactive sessions and in-depth discussions, you’ll learn how cutting-edge approaches — such as single-cell and spatial profiling, mathematical modeling and computational analysis — are transforming our understanding of clonal dynamics. Featured speakers will share insights into the forces driving cancer evolution, from genetic changes to microenvironmental influences, and how these factors contribute to therapeutic resistance. 

What Will be Discussed 

  • Mechanisms driving clonal evolution and tumor heterogeneity 
  • The role of microenvironmental factors in cancer progression 
  • Emerging technologies for single-cell and spatial analysis 
  • Computational and mathematical models for studying clonal dynamics 
  • Implications for therapeutic resistance and clinical outcomes 

Why attend? 

  • Gain a comprehensive view of clonal evolution and its role in cancer progression. 
  • Discover emerging technologies that enable cellular analysis of tumor heterogeneity. 
  • Engage with thought leaders and peers in a dynamic online format featuring live-streamed lectures and interactive Q&A sessions. 

Registration

Registration Open

Registration is complimentary.

Register Now

Event Contact

Ashley Mrdelja

People

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